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Today's top stories: The chair of the UK Vaccine Taskforce has said the first generation of COVID-19 vaccines "is likely to be imperfect" and "might not work for everyone", as researchers say 'significant gaps' in Test and Trace data is making it impossible to know if the government's scheme is reducing the spread of coronavirus. And Staffordshire is set to move into Tier 2 of COVID-19 restrictions following a continuing rise in cases.

Latest news, analysis and explainers here:
? First COVID vaccines 'likely to be imperfect' https://trib.al/bybxnHh
? Scientists warn of 'significant gaps' in England's Test and Trace data https://trib.al/JnIho3s
? Staffordshire to move into Tier 2 COVID-19 restrictions 'as soon as this weekend' https://trib.al/6lfysjs

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